Colon targeted drug delivery systems: Based on Polymers

Research on colon-targeted polymers delivery systems is ongoing for conditions such ulcerative colitis, Crohn's disease, colon cancer, as well the of peptide or protein medications and vaccines. For colon-specific disorders in particular, focused nano-drug to helpful because nanoparticles can build up sick areas, improve therapeutic efficacies, allow localized therapies, which lower systemic toxicity. The efficient NDDS colon, however, may be hampered by a number obstacles, including burst drug release, enzyme acidic degradation carrier stomach, pH fluctuations, mucus trapping, uptake upper small intestine. These obstacles might surmounted with improvements NDDS, resulting effective illnesses. This review provides an updated summary recent advances development orally administered targeting future advancements this research. It also discusses some potential challenges faced oral systems, areas.